Smart Skins

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003 | Research

     +   Skin Response to Injury

There are 3 degrees of skin injury.

1. Epidermal (1st degree)
2. Epidermal Plus (2nd degree)
3. Epidermal Plus near-full to full dermal (third degree)

Epidermal

• This layer can regenerate itself
• It heals by migration of keratinocytes from the wound.
• The stratum basale at wound and the keratinocytes proliferation help regenerate the epidermis

Epidermal Plus

• Note: the dermis can not regenerate. 
• Now, the dermis can sustain damage.
• The epidermal appendages will go into re-epithelialization, repairing the epidermis.
• This process will not repair the dermis, it will just be thinner.

Epidermal Plus near-full to full dermal

• The thicker layer (dermis) is completely destroyed.
• There is a proliferation of granulation tissue that goes into effect to merely cover up the expose part of the tissue
• this helps fight off infections
• If the burned/destroyed site is to large, then the fibroblasts of skin can not produce the collagen need to heal which limit the ability to close the wound. 
• Surgical procedures must step in to heal the wound. 

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